Neural signatures of autism spectrum disorders: insights into brain network dynamics.

ABSTRACT: Neuroimaging investigations of autism spectrum disorders (ASDs) have advanced our understanding of atypical brain function and structure, and have recently converged on a model of altered network-level connectivity. Traditional task-based functional magnetic resonance imaging (MRI) and volume-based structural MRI studies have identified widespread atypicalities in brain regions involved in social behavior and other core ASD-related behavioral deficits. More recent advances in MR-neuroimaging methods allow for quantification of brain connectivity using diffusion tensor imaging, functional connectivity, and graph theoretic methods. These newer techniques have moved the field toward a systems-level understanding of ASD etiology, integrating functional and structural measures across distal bra

SUBMITTER: Hernandez LM 

PROVIDER: S-EPMC4262896 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature