Graphene and other nanomaterial-based electrochemical aptasensors.

ABSTRACT: Electrochemical aptasensors, which are based on the specificity of aptamer-target recognition, with electrochemical transduction for analytical purposes have received particular attention due to their high sensitivity and selectivity, simple instrumentation, as well as low production cost. Aptamers are functional nucleic acids with specific and high affinity to their targets, similar to antibodies. However, they are completely selected in vitro in contrast to antibodies. Due to their stability, easy chemical modifications and proneness to nanostructured device construction, aptamer-based sensors have been incorporated in a variety of applications including electrochemical sensing devices. In recent years, the performance of aptasensors has been augmented by incorporating novel nanomaterial

SUBMITTER: Hernandez FJ 

PROVIDER: S-EPMC4263542 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature