State of the art: Response assessment in lung cancer in the era of genomic medicine.

ABSTRACT: Tumor response assessment has been a foundation for advances in cancer therapy. Recent discoveries of effective targeted therapy for specific genomic abnormalities in lung cancer and their clinical application have brought revolutionary advances in lung cancer therapy and transformed the oncologist's approach to patients with lung cancer. Because imaging is a major method of response assessment in lung cancer both in clinical trials and practice, radiologists must understand the genomic alterations in lung cancer and the rapidly evolving therapeutic approaches to effectively communicate with oncology colleagues and maintain the key role in lung cancer care. This article describes the origin and importance of tumor response assessment, presents the recent genomic discoveries in lung cancer

SUBMITTER: Nishino M 

PROVIDER: S-EPMC4263630 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature