Oral human papillomavirus (HPV) infection in HPV-positive patients with oropharyngeal cancer and their partners.

ABSTRACT:

Purpose

To better understand oral human papillomavirus (HPV) infection and cancer risk among long-term sexual partners of patients with HPV-positive oropharyngeal cancer (HPV-OPC).

Patients and methods

An oral rinse sample, risk factor survey, cancer history, and oral examination (partners only) were collected from patients with HPV-OPC and their partners. Oral rinse samples were evaluated for 36 types of HPV DNA using PGMY 09/11 primers and line-blot hybridization and HPV16 copy number using quantitative polymerase chain reaction. Oral HPV prevalence was compared with infection among those age 45 to 65 years using National Health and Nutrition Examination Survey (NHANES) 2009-2010.

Results

A total of 164 patients with HPV-OPC and 93 of their partners were enrolled. P

SUBMITTER: D'Souza G 

PROVIDER: S-EPMC4263818 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature