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ABSTRACT: Background
In recent years novel human respiratory disease agents have been described for Southeast Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses with a strong phylogenetic relationship to orthoreoviruses of bat origin.Results
In this report, we isolated a novel Melaka-like reovirus (named "Cangyuan virus") from intestinal content samples of one fruit bat residing in China's Yunnan province. Phylogenetic analysis of the whole Cangyuan virus genome sequences of segments L, M and S demonstrated the genetic diversity of the Cangyuan virus. In contrast to the L and M segments, the phylogenetic trees for the S segments of Cangyuan virus demonstrated a greater degree of heterogeneity.Conclusions
Phylogenetic analysis indicated that the Cangyuan virus was a novel orthoreovirus and substantially different from currently known members of Pteropine orthoreovirus (PRV) species group.
SUBMITTER: Hu T
PROVIDER: S-EPMC4264558 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Hu Tingsong T Qiu Wei W He Biao B Zhang Yan Y Yu Jing J Liang Xiu X Zhang Wendong W Chen Gang G Zhang Yingguo Y Wang Yiyin Y Zheng Ying Y Feng Ziliang Z Hu Yonghe Y Zhou Weiguo W Tu Changchun C Fan Quanshui Q Zhang Fuqiang F
BMC microbiology 20141130
<h4>Background</h4>In recent years novel human respiratory disease agents have been described for Southeast Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses with a strong phylogenetic relationship to orthoreoviruses of bat origin.<h4>Results</h4>In this report, we isolated a novel Melaka-like reovirus (named "Cangyuan virus") from intestinal content samples of one fruit bat residing in China's Yunnan province. Phylogenetic analysis of the whole Cangyuan vi ...[more]