Ideal resuscitation pressure for uncontrolled hemorrhagic shock in different ages and sexes of rats.

ABSTRACT:

Introduction

Our previous studies demonstrated that 50-60 mmHg mean arterial blood pressure was the ideal target hypotension for uncontrolled hemorrhagic shock during the active hemorrhage in sexually mature rats. The ideal target resuscitation pressure for immature and older rats has not been determined.

Methods

To elucidate this issue, using uncontrolled hemorrhagic-shock rats of different ages and sexes (6 weeks, 14 weeks and 1.5 years representing pre-adult, adult and older rats, respectively), the resuscitation effects of different target pressures (40, 50, 60, 70 and 80 mmHg) on uncontrolled hemorrhagic shock during active hemorrhage and the age and sex differences were observed.

Results

Different target resuscitation pressures had different resuscitation outcom

SUBMITTER: Li T 

PROVIDER: S-EPMC4264615 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature