Clinicopathological and prognostic significance of CD24 overexpression in patients with gastric cancer: a meta-analysis.

ABSTRACT:

Objective

The prognostic significance of CD24 expression for survival in patients with gastric cancer remains controversial. We conducted a meta-analysis to investigate the impact of CD24 expression on clinicopathological features and survival outcomes in gastric cancer.

Methods

A comprehensive literature search of the electronic databases PubMed, Embase, Web of Science and China National Knowledge Infrastructure (CNKI; up to April 8, 2014) was performed for relevant studies using multiple search strategies. Correlations between CD24 expression and clinicopathological features and overall survival (OS) were analyzed.

Results

A total of 1,041 patients with gastric cancer from 9 studies were included. The pooled odds ratios (ORs) indicated CD24 expression was associated

SUBMITTER: Wu JX 

PROVIDER: S-EPMC4264770 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature