Appropriate revascularization in stable angina: lessons from the BARI 2D trial.

ABSTRACT:

Background

The 2012 Guidelines for Diagnosis and Management of Patients with Stable Ischemic Heart Disease recommend intensive antianginal and risk factor treatment (optimal medical management [OMT]) before considering revascularization to relieve symptoms. The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial randomized patients with ischemic heart disease and anatomy suitable to revascularization to (1) initial OMT with revascularization if needed or (2) initial revascularization plus OMT and found no difference in major cardiovascular events. Ultimately, however, 37.9% of the OMT group was revascularized during the 5-year follow-up period.

Methods

Data from the 1192 patients randomized to OMT were analyzed to identify subgroups in which the inc

SUBMITTER: Krone RJ 

PROVIDER: S-EPMC4265566 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature