Ontology highlight
ABSTRACT:
SUBMITTER: Gotoh S
PROVIDER: S-EPMC4266003 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Stem cell reports 20140821 3
No methods for isolating induced alveolar epithelial progenitor cells (AEPCs) from human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) have been reported. Based on a study of the stepwise induction of alveolar epithelial cells (AECs), we identified carboxypeptidase M (CPM) as a surface marker of NKX2-1(+) "ventralized" anterior foregut endoderm cells (VAFECs) in vitro and in fetal human and murine lungs. Using SFTPC-GFP reporter hPSCs and a 3D coculture system with fet ...[more]