Prediction accuracy of a novel dynamic structure-function model for glaucoma progression.

ABSTRACT:

Purpose

To assess the prediction accuracy of a novel dynamic structure-function (DSF) model to monitor glaucoma progression.

Methods

Longitudinal data of paired rim area (RA) and mean sensitivity (MS) from 220 eyes with ocular hypertension or primary open-angle glaucoma enrolled in the Diagnostic Innovations in Glaucoma Study or the African Descent and Glaucoma Evaluation Study were included. Rim area and MS were expressed as percent of mean normal based on an independent dataset of 91 healthy eyes. The DSF model uses centroids as estimates of the current state of the disease and velocity vectors as estimates of direction and rate of change over time. The first three visits were used to predict the fourth visit; the first four visits were used to predict the fifth visit, and

SUBMITTER: Hu R 

PROVIDER: S-EPMC4266083 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature