Neuroplasticity-based auditory training via laptop computer improves cognition in young individuals with recent onset schizophrenia.

ABSTRACT:

Objective

Cognitive deficits that characterize schizophrenia are present in the prodrome, worsen with illness onset, and predict functional outcome. Cognitive dysfunction is thus a critical target for early intervention in young individuals with recent onset schizophrenia.

Method

This 2-site double-blind randomized controlled trial investigated cognitive training of auditory processing/verbal learning in 86 subjects with recent onset schizophrenia (mean age of 21 years). Subjects were given laptop computers to take home and were asked to perform 40 hours of training or 40 hours of commercial computer games over 8 weeks. We examined cognitive measures recommended by the Measurement and Treatment Research to Improve Cognition in Schizophrenia initiative (MATRICS), symptoms, an

SUBMITTER: Fisher M 

PROVIDER: S-EPMC4266283 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature