Maximal standard dose of parenteral iron for hemodialysis patients: an MRI-based decision tree learning analysis.

ABSTRACT:

Background and objectives

Iron overload used to be considered rare among hemodialysis patients after the advent of erythropoesis-stimulating agents, but recent MRI studies have challenged this view. The aim of this study, based on decision-tree learning and on MRI determination of hepatic iron content, was to identify a noxious pattern of parenteral iron administration in hemodialysis patients.

Design, setting, participants and measurements

We performed a prospective cross-sectional study from 31 January 2005 to 31 August 2013 in the dialysis centre of a French community-based private hospital. A cohort of 199 fit hemodialysis patients free of overt inflammation and malnutrition were treated for anemia with parenteral iron-sucrose and an erythropoesis-stimulating agent (darb

SUBMITTER: Rostoker G 

PROVIDER: S-EPMC4266677 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature