Controlled-release oxycodone versus naproxen at home after ambulatory surgery: a randomized controlled trial.

ABSTRACT:

Background

Strong opioids in the home setting after ambulatory surgery have rarely been studied for fear of hazardous adverse effects such as respiratory depression.

Objectives

We compared the efficacy of paracetamol/controlled-release (CR) oxycodone and paracetamol/naproxen for treatment of acute postoperative pain at home after ambulatory surgery. Secondary outcomes were adverse effects of study medication, treatment satisfaction, and postoperative analgesic compliance.

Methods

Patients undergoing ambulatory knee arthroscopy or inguinal hernia repair surgery (n = 105) were randomized into 3 groups: Group1 paracetamol/naproxen (n = 35), Group 2 paracetamol/CR oxycodone for 24 hours (n = 35), and Group 3 paracetamol/CR oxycodone for 48 hours (n = 35). Pain intensity a

SUBMITTER: Stessel B 

PROVIDER: S-EPMC4266769 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature