Silk-based resorbable electronic devices for remotely controlled therapy and in vivo infection abatement.

ABSTRACT: A paradigm shift for implantable medical devices lies at the confluence between regenerative medicine, where materials remodel and integrate in the biological milieu, and technology, through the use of recently developed material platforms based on biomaterials and bioresorbable technologies such as optics and electronics. The union of materials and technology in this context enables a class of biomedical devices that can be optically or electronically functional and yet harmlessly degrade once their use is complete. We present here a fully degradable, remotely controlled, implantable therapeutic device operating in vivo to counter a Staphylococcus aureus infection that disappears once its function is complete. This class of device provides fully resorbable packaging and electronics that c

SUBMITTER: Tao H 

PROVIDER: S-EPMC4267401 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature