Validation of outlier loci through replication in independent data sets: a test on Arabis alpina.

ABSTRACT: Outlier detection and environmental association analysis are common methods to search for loci or genomic regions exhibiting signals of adaptation to environmental factors. However, a validation of outlier loci and corresponding allele distribution models through functional molecular biology or transplant/common garden experiments is rarely carried out. Here, we employ another method for validation, namely testing outlier loci in specifically designed, independent data sets. Previously, an outlier locus associated with three different habitat types had been detected in Arabis alpina. For the independent validation data set, we sampled 30 populations occurring in these three habitat types across five biogeographic regions of the Swiss Alps. The allele distribution model found in the origina

SUBMITTER: Buehler D 

PROVIDER: S-EPMC4267868 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature