Liver involvement in early autosomal-dominant polycystic kidney disease.

ABSTRACT:

Background & aims

Polycystic liver disease (PLD), the most common extrarenal manifestation of autosomal-dominant polycystic kidney disease (ADPKD), has become more prevalent as a result of increased life expectancy, improved renal survival, reduced cardiovascular mortality, and renal replacement therapy. No studies have fully characterized PLD in large cohorts. We investigated whether liver and cyst volumes are associated with volume of the hepatic parenchyma, results from liver laboratory tests, and patient-reported outcomes.

Methods

We performed a cross-sectional analysis of baseline liver volumes, measured by magnetic resonance imaging, and their association with demographics, results from liver laboratory and other tests, and quality of life. The data were collected from

SUBMITTER: Hogan MC 

PROVIDER: S-EPMC4267913 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature