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Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster.


ABSTRACT: Within species, levels of gene expression typically vary greatly between tissues, sexes, individuals, and populations. To investigate gene expression variation between sexes and populations in a single somatic tissue, we performed a quantitative analysis of the Malpighian tubule transcriptome in adult males and females of Drosophila melanogaster derived from two distinct populations (one from sub-Saharan Africa and one from northern Europe). We identified 2308 genes that differed in expression between the sexes and 2474 genes that differed in expression between populations at a false discovery rate of 5%. We also identified more than 1000 genes that showed a sex-by-population interaction in their expression. The genes that differed in expression between sexes showed enrichment for a wide v

SUBMITTER: Huylmans AK 

PROVIDER: S-EPMC4267927 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature