Ontology highlight
ABSTRACT:
SUBMITTER: Pan K
PROVIDER: S-EPMC4268701 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Nature communications 20141203
DNA can be programmed to self-assemble into high molecular weight 3D assemblies with precise nanometer-scale structural features. Although numerous sequence design strategies exist to realize these assemblies in solution, there is currently no computational framework to predict their 3D structures on the basis of programmed underlying multi-way junction topologies constrained by DNA duplexes. Here, we introduce such an approach and apply it to assemblies designed using the canonical immobile fou ...[more]