Analysis of codon usage pattern in Taenia saginata based on a transcriptome dataset.

ABSTRACT:

Background

Codon usage bias is an important evolutionary feature in a genome and has been widely documented in many genomes. Analysis of codon usage bias has significance for mRNA translation, design of transgenes, new gene discovery, and studies of molecular biology and evolution, etc. However, the information about synonymous codon usage pattern of T. saginata genome remains unclear. T. saginata is a food-borne zoonotic cestode which infects approximataely 50 million humans worldwide, and causes significant health problems to the host and considerable socio-economic losses as a consequence. In this study, synonymous codon usage in T. saginata were examined.

Methods

Total RNA was isolated from T. saginata cysticerci and 91,487 unigenes were generated using Illumina sequenci

SUBMITTER: Yang X 

PROVIDER: S-EPMC4268816 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature