Associations between inflammation and cognitive function in African Americans and European Americans.

ABSTRACT:

Objectives

To examine associations between specific inflammatory biomarkers and cognitive function in African Americans (AAs) and European Americans (EAs) with prevalent vascular risk factors.

Design

Cross-sectional analysis using generalized estimating equations to account for familial clustering; standardized β-coefficients, adjusted for age, sex, and education are reported.

Setting

Community cohort study in Jackson, Mississippi, and Rochester, Minnesota.

Participants

Genetic Epidemiology Network of Arteriopathy (GENOA)-Genetics of Microangiopathic Brain Injury (GMBI) Study participants.

Measurements

Associations between inflammation (high-sensitivity C-reactive protein (CRP), interleukin (IL)-6, soluble tumor necrosis factor (TNF) receptor 1 and 2 (sT

SUBMITTER: Windham BG 

PROVIDER: S-EPMC4270090 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature