DBBP: database of binding pairs in protein-nucleic acid interactions.

ABSTRACT:

Background

Interaction of proteins with other molecules plays an important role in many biological activities. As many structures of protein-DNA complexes and protein-RNA complexes have been determined in the past years, several databases have been constructed to provide structure data of the complexes. However, the information on the binding sites between proteins and nucleic acids is not readily available from the structure data since the data consists mostly of the three-dimensional coordinates of the atoms in the complexes.

Results

We analyzed the huge amount of structure data for the hydrogen bonding interactions between proteins and nucleic acids and developed a database called DBBP (DataBase of Binding Pairs in protein-nucleic acid interactions, http://bclab.inha.ac.k

SUBMITTER: Park B 

PROVIDER: S-EPMC4271565 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature