Modification of biomaterials with a self-protein inhibits the macrophage response.

ABSTRACT: A biomaterial inhibits the host immune response by displaying an endo-genously expressed immunomodulatory molecule, CD200. Immobilization of CD200 onto biomaterial surfaces effectively suppresses macrophage activation and reduces inflammatory response to subcutaneously implanted materials.

SUBMITTER: Kim YK 

PROVIDER: S-EPMC4272238 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature