Identification of skin-expressed genes possibly associated with wool growth regulation of Aohan fine wool sheep.

ABSTRACT:

Background

Sheep are valuable resources for the animal fibre industry. Therefore, identifying genes which regulate wool growth would offer strategies for improving the quality of fine wool. In this study, we employed Agilent sheep gene expression microarray and proteomic technology to compare the gene expression patterns of the body side (hair-rich) and groin (hairless) skins of Aohan fine wool sheep (a Chinese indigenous breed).

Results

Comparing the body side to the groin skins (S/G) of Aohan fine wool sheep, the microarray study revealed that 1494 probes were differentially expressed, including 602 more highly expressed and 892 less highly expressed probes. The microarray results were verified by means of quantitative PCR. Cluster analysis could distinguish the body side

SUBMITTER: Liu N 

PROVIDER: S-EPMC4272822 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature