Blunted striatal responses to favorite-food cues in smokers.

ABSTRACT:

Background

Although tobacco-smoking is associated with relatively leaner body mass and smoking cessation with weight gain, the brain mechanisms underlying these relationships are not well understood. Smokers compared to non-smokers have shown diminished neural responses to non-tobacco rewarding stimuli (e.g., monetary rewards), but brain responses to favorite-food cues have not been investigated relative to smoking status. We hypothesized that smokers would exhibit diminished neural responses compared to non-smokers in response to favorite-food cues in motivation-reward and emotion-regulating regions of the brain.

Methods

Twenty-three smokers and 23 non-smokers matched based on body mass index (BMI), age, and gender listened to personalized favorite-food cue, stress, and neu

SUBMITTER: Jastreboff AM 

PROVIDER: S-EPMC4272899 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature