Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4.

ABSTRACT: The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates. Thioglycosides and glycosyl trichloroacetimidate derivatives have been used as glycosyl donors in the glycosylations.

SUBMITTER: Mandal PK 

PROVIDER: S-EPMC4273275 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature