A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes.

ABSTRACT: This work reports the synthesis of a new family of mono-substituted amphiphilic cyclodextrins using a green methodology. Reactions using greener and safer catalysts with more environmentally friendly purification solvents were performed. Four unreported mono-substituted cyclodextrins bearing a phytosphingolipidyl chain and a fatty acid chain (C10, C12, C14 and C18) were successfully obtained with a promising yield.

SUBMITTER: Miao Y 

PROVIDER: S-EPMC4273305 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature