When to stop septic shock resuscitation: clues from a dynamic perfusion monitoring.

ABSTRACT:

Background

The decision of when to stop septic shock resuscitation is a critical but yet a relatively unexplored aspect of care. This is especially relevant since the risks of over-resuscitation with fluid overload or inotropes have been highlighted in recent years. A recent guideline has proposed normalization of central venous oxygen saturation and/or lactate as therapeutic end-points, assuming that these variables are equivalent or interchangeable. However, since the physiological determinants of both are totally different, it is legitimate to challenge the rationale of this proposal. We designed this study to gain more insights into the most appropriate resuscitation goal from a dynamic point of view. Our objective was to compare the normalization rates of these and other poten

SUBMITTER: Hernandez G 

PROVIDER: S-EPMC4273696 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature