Increased coronary vessel wall thickness in HIV-infected young adults.

ABSTRACT:

Background

Individuals with long-term human immunodeficiency virus (HIV) infection are at risk for premature vasculopathy and cardiovascular disease (CVD). We evaluated coronary vessel wall thickening, coronary plaque, and epicardial fat in patients infected with HIV early in life compared with healthy controls.

Methods

This is a prospective cross-sectional study of 35 young adults who acquired HIV in early life and 11 healthy controls, free of CVD. Time resolved phase-sensitive dual inversion recovery black-blood vessel wall magnetic resonance imaging (TRAPD) was used to measure proximal right coronary artery (RCA) wall thickness, and multidetector computed tomography (CT) angiography was used to quantify coronary plaque and epicardial fat.

Results

RCA vessel wall th

SUBMITTER: Abd-Elmoniem KZ 

PROVIDER: S-EPMC4274345 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature