Minimally important difference for the Expanded Prostate Cancer Index Composite Short Form.

ABSTRACT:

Objective

To establish a score threshold that constitutes a clinically relevant change for each domain of the Expanded Prostate Cancer Index Composite (EPIC) Short Form (EPIC-26). Although its use in clinical practice and clinical trials has increased worldwide, the clinical interpretation of this 26-item disease-specific patient-reported quality of life questionnaire for men with localized prostate cancer would be facilitated by characterization of score thresholds for clinically relevant change (the minimally important differences [MIDs]).

Methods

We used distribution- and anchor-based approaches to establish the MID range for each EPIC-26 domain (urinary, sexual, bowel, and vitality/hormonal) based on a prospective multi-institutional cohort of 1201 men treated for prosta

SUBMITTER: Skolarus TA 

PROVIDER: S-EPMC4274392 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature