Association between body mass index and risk of total knee replacement, the Singapore Chinese Health Study.

ABSTRACT:

Purpose

Data on the association between body mass index (BMI) and risk of knee osteoarthritis (KOA) are sparse for Asian populations who are leaner than Western populations. We evaluated the association between BMI and risk of total knee replacement (TKR) due to severe KOA among Chinese in Singapore.

Methods

We used data from the Singapore Chinese Health Study (SCHS), a population-based prospective cohort of 63,257 Chinese men and women, aged 45-74 years at enrollment from 1993 to 1998. Information on height, weight, diet and lifestyle factors were obtained via in-person interviews. TKR cases for severe KOA were identified via linkage with the nationwide hospital discharge database through 2011. Cox regression and weighted least squares regression were used in the analysis.<

SUBMITTER: Leung YY 

PROVIDER: S-EPMC4275403 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature