Risk factors for acute exacerbations of COPD in a primary care population: a retrospective observational cohort study.

ABSTRACT:

Objectives

To evaluate risk factors associated with exacerbation frequency in primary care. Information on exacerbations of chronic obstructive pulmonary disease (COPD) has mainly been generated by secondary care-based clinical cohorts.

Design

Retrospective observational cohort study.

Setting

Electronic medical records database (England and Wales).

Participants

58,589 patients with COPD aged ≥40 years with COPD diagnosis recorded between 1 April 2009 and 30 September 2012, and with at least 365 days of follow-up before and after the COPD diagnosis, were identified in the Clinical Practice Research Datalink. Mean age: 69 years; 47% female; mean forced expiratory volume in 1s 60% predicted.

Outcome measures

Data on moderate or severe exacerbation episodes

SUBMITTER: Mullerova H 

PROVIDER: S-EPMC4275672 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature