Functional-structural correlations in the afferent visual pathway in pediatric demyelination.

ABSTRACT:

Objective

We evaluated the relationship of optical coherence tomography (OCT)-measured ganglion cell layer (GCL) and retinal nerve fiber layer (RNFL) thickness to other functional measures of afferent visual pathway competence including high-contrast visual acuity (HCVA) and low-contrast visual acuity (LCVA), visual field sensitivity, and color vision perception in a pediatric population with demyelinating disorders.

Methods

This was a cross-sectional evaluation of 37 children, aged 8-18 years, with pediatric demyelinating disorders (n = 74 eyes), and 18 healthy controls (n = 36 eyes), who were recruited from the University of Toronto, Hospital for Sick Children and the University of Calgary, Alberta Children's Hospital, Canada. A standardized visual battery, including spect

SUBMITTER: Yeh EA 

PROVIDER: S-EPMC4276407 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature