Assessing cellular response to functionalized α-helical peptide hydrogels.

ABSTRACT: α-Helical peptide hydrogels are decorated with a cell-binding peptide motif (RGDS), which is shown to promote adhesion, proliferation, and differentiation of PC12 cells. Gel structure and integrity are maintained after functionalization. This opens possibilities for the bottom-up design and engineering of complex functional scaffolds for 2D and 3D cell cultures.

SUBMITTER: Mehrban N 

PROVIDER: S-EPMC4276410 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature