Neuropsychological functioning and health-related quality of life: pediatric acute liver failure study group results.

ABSTRACT:

Objectives

Pediatric acute liver failure (PALF) is a rare but serious event, with poorly understood functional outcomes. The goal was to determine the prevalence of reduced neuropsychological functioning and health-related quality of life (HRQOL) following PALF.

Methods

This multicenter study examined neuropsychological functioning and HRQOL 1 to 6 (median 3.8) years after PALF. Participants ages 6 to 16 (median 9.9) years were recruited from the PALF registry and administered measures of intelligence, visual spatial/visual motor coordination, attention, executive function, depression, and adaptive skills. HRQOL and fatigue were assessed using the Pediatric Quality of Life Inventory 4.0 Generic Core Scales (PedsQL 4.0) and PedsQL Multidimensional Fatigue Scale.

Results

SUBMITTER: Sorensen LG 

PROVIDER: S-EPMC4276462 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature