Performance of real-time elastography for the staging of hepatic fibrosis: a meta-analysis.

ABSTRACT:

Background

With the rapid development of real-time elastography (RTE), a variety of measuring methods have been developed for the assessment of hepatic fibrosis. We evaluated the overall performance of four methods based on RTE by performing meta-analysis of published literature.

Methods

Online journal databases and a manual search from April 2000 to April 2014 were used. Studies from different databases that meet inclusion criteria were enrolled. The statistical analysis was performed using a random-effects model and fixed-effects model for the overall effectiveness of RTE. The area under the receiver operating characteristic curve (AUROC) was calculated for various means. Fagan plot analysis was used to estimate the clinical utility of RTE, and the heterogeneity of the stu

SUBMITTER: Hong H 

PROVIDER: S-EPMC4277316 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature