Enantioselective selenocyclization via dynamic kinetic resolution of seleniranium ions by hydrogen-bond donor catalysts.

ABSTRACT: Highly enantioselective selenocyclization reactions are promoted by the combination of a new chiral squaramide catalyst, a mineral acid, and an achiral Lewis base. Mechanistic studies reveal that the enantioselectivity originates from the dynamic kinetic resolution of seleniranium ions through anion-binding catalysis.

SUBMITTER: Zhang H 

PROVIDER: S-EPMC4277748 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature