Aptamer-based cell imaging reagents capable of fluorescence switching.

ABSTRACT: We describe an aptamer-conjugated polydiacetylene imaging probe (ACP) that shows highly specific fluorescence switching upon binding to epithelial cancer cells that overexpress the tumor biomarker protein EpCAM (epithelial cell adhesion molecule) on their surface.

SUBMITTER: Jung YK 

PROVIDER: S-EPMC4277889 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature