Vitamin D status modifies the association between statin use and musculoskeletal pain: a population based study.

ABSTRACT:

Background

Past studies examining the effect of vitamin D on statin myalgia have been variable; however, these studies were done in limited samples not representative of the general population. We aimed to evaluate whether vitamin D status modifies the association between statin use and musculoskeletal pain in a sample representative of the general population.

Methods

We conducted a cross-sectional study using the National Health and Nutrition Examination Survey 2001-2004. Musculoskeletal symptoms and statin use were self-reported. Vitamin D status was assessed using serum 25 hydroxyvitamin D (25[OH]D), categorized as <15 ng/mL or ≥15 ng/mL. To evaluate if vitamin D status modifies the association between statin use and prevalent musculoskeletal pain, we performed multivaria

SUBMITTER: Morioka TY 

PROVIDER: S-EPMC4277894 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature