Reliability, validity and treatment sensitivity of the Schizophrenia Cognition Rating Scale.

ABSTRACT: Cognitive functioning can be assessed with performance-based assessments such as neuropsychological tests and with interview-based assessments. Both assessment methods have the potential to assess whether treatments for schizophrenia improve clinically relevant aspects of cognitive impairment. However, little is known about the reliability, validity and treatment responsiveness of interview-based measures, especially in the context of clinical trials. Data from two studies were utilized to assess these features of the Schizophrenia Cognition Rating Scale (SCoRS). One of the studies was a validation study involving 79 patients with schizophrenia assessed at 3 academic research centers in the US. The other study was a 32-site clinical trial conducted in the US and Europe comparing the effect

SUBMITTER: Keefe RS 

PROVIDER: S-EPMC4277931 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature