Does premedication with dexmedetomidine provide perioperative hemodynamic stability in hypertensive patients?

ABSTRACT:

Background

Perioperative hemodynamic fluctuations are seen more often in hypertensive patients than in normotensive patients. The purpose of our study was to investigate the perioperative hemodynamic effects of dexmedetomidine and midazolam used for premedication in hypertensive patients relative to each other and in comparison to normotensive patients.

Methods

One-hundred-forty female, normotensive or hypertensive patients undergoing myomectomies or hysterectomies. They were randomly enrolled into the subgroups: Group ND (normotensive-dexmedetomidine); Group HD (hypertensive-dexmedetomine); Group NM (normotensive-midazolam); Group HM (hypertensive- midazolam). Dexmedetomidine was administered at a concentration of 0.5 μg.kg(-1), and midazolam was administered at a concentra

SUBMITTER: Sezen G 

PROVIDER: S-EPMC4279802 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature