Statin therapy decreased the recurrence frequency of atrial fibrillation after electrical cardioversion: a meta-analysis.

ABSTRACT:

Background

It is unclear whether statin agents provide clinical benefit in preventing the relapse of atrial fibrillation (AF) after electrical cardioversion (EC). The purpose of this study was to assess the effect of statin agents on the recurrence of AF after EC by conducting a meta-analysis of randomized controlled trials (RCTs).

Material and methods

We conducted a systematic literature search of Medline, EMBASE, ISI Web of Science, and Cochrane databases. RCTs comparing clinical endpoint of the recurrence of AF associated with statin administration vs. no statin treatment (placebo or conventional medical therapy) in patients with AF after EC were eligible. Combined results are presented as risk ratios (RRs) with 95% confidence intervals (CIs).

Results

A total of 5

SUBMITTER: Yan P 

PROVIDER: S-EPMC4280056 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature