Phylogenetic analysis of neuraminidase gene of H9N2 avian influenza viruses isolated from chicken in Iran during 2010-2011.

ABSTRACT: BACKGROUNDS AND OBJECTIVES:Classified as low pathogenic avian influenza (LPAI) viruses, the H9N2 subtype causes severe respiratory disease in poultry farms and occasional respiratory disease in humans. In this study, the neuraminidase (NA) gene of three Avian Influenza (AI) H9N2 strains isolated from poultry farms in Iran during 2010-11, as well as other reported Iranian H9N2 isolates, were genetically analyzed and their nucleotide changes were evaluated. MATERIALS AND METHODS:The NA gene of three AIVs were sequenced and evaluated for genetic characteristics and phylogenetic relationship. RESULTS:One new potential glycosylation site (PGS) at amino acid position 306 was observed in one of the studied isolates (A/Chicken/Iran/N102/2011). Antigenic sites of NA in Iranian H9N2 isolates have va

SUBMITTER: Norouzian H 

PROVIDER: S-EPMC4281667 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature