Blood glucose concentration and risk of pancreatic cancer: systematic review and dose-response meta-analysis.

ABSTRACT:

Objective

To evaluate potential linear and non-linear dose-response relations between blood glucose and risk of pancreatic cancer.

Design

Systematic review and dose-response meta-analysis of prospective observational studies.

Data sources

Search of PubMed, Scopus, and related reviews before 30 November 2013 without language restriction.

Eligibility criteria

Prospective studies evaluating the association between blood glucose concentration and pancreatic cancer. Retrospective and cross sectional studies excluded to avoid reverse causality.

Data extraction and synthesis

Two reviewers independently extracted relevant information and assessed study quality with the Newcastle-Ottawa scale. Random effects dose-response meta-analysis was conducted to assess pot

SUBMITTER: Liao WC 

PROVIDER: S-EPMC4282179 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature