A Systematic Review of the Benefits and Risks of Anticoagulation Following Traumatic Brain Injury.

ABSTRACT:

Objective

To synthesize the existing literature on benefits and risks of anticoagulant use after traumatic brain injury (TBI).

Design

Systematic review. A literature search was performed in MEDLINE, International Pharmaceutical Abstracts, Health Star, and CINAHL (Cumulative Index to Nursing and Allied Health Literature) on October 11, 2012, and updated on September 2, 2013, using terms related to TBI and anticoagulants.

Main measures

Human studies evaluating the effects of post-TBI anticoagulation on venous thromboembolism, hemorrhage, mortality, or coagulation parameters with original analyses were eligible for the review. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline was followed throughout the conduct of the review.

Result

SUBMITTER: Shen X 

PROVIDER: S-EPMC4282634 | biostudies-literature | 2015 Jul-Aug

REPOSITORIES: biostudies-literature