Standardization and validation of a novel and simple method to assess lumbar dural sac size.

ABSTRACT:

Aim

To develop and validate a simple, reproducible method to assess dural sac size using standard imaging technology.

Materials and methods

This study was institutional review board-approved. Two readers, blinded to the diagnoses, measured anterior-posterior (AP) and transverse (TR) dural sac diameter (DSD), and AP vertebral body diameter (VBD) of the lumbar vertebrae using MRI images from 53 control patients with pre-existing MRI examinations, 19 prospectively MRI-imaged healthy controls, and 24 patients with Marfan syndrome with prior MRI or CT lumbar spine imaging. Statistical analysis utilized linear and logistic regression, Pearson correlation, and receiver operating characteristic (ROC) curves.

Results

AP-DSD and TR-DSD measurements were reproducible between two

SUBMITTER: Daniels ML 

PROVIDER: S-EPMC4282821 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature