Relationship between 17-hydroxyprogesterone responses to human chorionic gonadotropin and markers of ovarian follicle morphology in women with polycystic ovary syndrome.

ABSTRACT:

Context

Women with polycystic ovary syndrome (PCOS) have increased 17-hydroxyprogesterone (17-OHP) responses to gonadotropin stimulation although individual variability is substantial, as reflected by exaggerated as well as normal responses. The relationship between 17-OHP responses to gonadotropin stimulation and markers of ovarian function has not been assessed.

Objective

To determine whether 17-OHP responses are associated with antral follicle count (AFC), anti-Mullerian hormone (AMH), or inhibin B (Inh B) levels in PCOS and normal women.

Design

Prospective study.

Setting

Research center at an academic medical center.

Participants

Women with PCOS (n = 18) and normal controls (n = 18).

Interventions

Blood samples were obtained before and 24 hour

SUBMITTER: Maas KH 

PROVIDER: S-EPMC4283019 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature