Preoperative assessment of high-risk candidates to predict survival after heart transplantation.

ABSTRACT:

Background

Alternate waiting list strategies expand listing criteria for patients awaiting heart transplantation (HTx). We retrospectively analyzed clinical events and outcome of patients listed as high-risk recipients for HTx.

Methods and results

We analyzed 822 adult patients who underwent HTx of whom 111 patients met high-risk criteria. Clinical data were collected from medical records and outcome factors calculated for 61 characteristics. Significant factors were summarized in a prognostic score. Age >65 years (67%) and amyloidosis (19%) were the most common reasons for alternate listing. High-risk recipients were older (63.2±10.2 versus 51.4±11.8 years; P<0.001), had more renal dysfunction, prior cancer, and smoking. Survival analysis revealed lower post-HTx survival in

SUBMITTER: Schulze PC 

PROVIDER: S-EPMC4283202 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature