Epidemiological and viral genome characteristics of the first human H7N9 influenza infection in Guangdong Province, China.

ABSTRACT:

Background

The first H7N9 human case in south of China was confirmed in Guangdong Province on August 2013, outside of the typical influenza season. For investigating the H7N9 virus source and transmission in the local community, we analyze the epidemiology and genome features of the virus isolated from the first human infection detected in Guangdong Province.

Methods

The data including medical records, exposure history and time line of events for the H7N9 patient and close contacts was collected. Variation and genetic signatures of H7N9 virus in Guangdong was analyzed using ClustalW algorithm and comparison with mutations associated with changes in biological characteristics of the virus.

Results

The female patient had a history of poultry exposure, and she was transf

SUBMITTER: Yang ZF 

PROVIDER: S-EPMC4283329 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature