Disease progression in hemodynamically stable patients presenting to the emergency department with sepsis.

ABSTRACT:

Background

Aggressive diagnosis and treatment of patients presenting to the emergency department (ED) with septic shock has been shown to reduce mortality. To enhance the ability to intervene in patients with lesser illness severity, a better understanding of the natural history of the early progression from simple infection to more severe illness is needed.

Objectives

The objectives were to 1) describe the clinical presentation of ED sepsis, including types of infection and causative microorganisms, and 2) determine the incidence, patient characteristics, and mortality associated with early progression to septic shock among ED patients with infection.

Methods

This was a multicenter study of adult ED patients with sepsis but no evidence of shock. Multivariable logisti

SUBMITTER: Glickman SW 

PROVIDER: S-EPMC4283798 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature