Cerebral near infrared spectroscopy oximetry in extremely preterm infants: phase II randomised clinical trial.

ABSTRACT:

Objective

To determine if it is possible to stabilise the cerebral oxygenation of extremely preterm infants monitored by cerebral near infrared spectroscopy (NIRS) oximetry.

Design

Phase II randomised, single blinded, parallel clinical trial.

Setting

Eight tertiary neonatal intensive care units in eight European countries.

Participants

166 extremely preterm infants born before 28 weeks of gestation: 86 were randomised to cerebral NIRS monitoring and 80 to blinded NIRS monitoring. The only exclusion criterion was a decision not to provide life support.

Interventions

Monitoring of cerebral oxygenation using NIRS in combination with a dedicated treatment guideline during the first 72 hours of life (experimental) compared with blinded NIRS oxygenation monito

SUBMITTER: Hyttel-Sorensen S 

PROVIDER: S-EPMC4283997 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature